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課程名稱 |
核醣核酸生物學
Rna Biology |
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開課學期 |
105-2 |
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授課對象 |
生命科學院 生命科學所 |
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授課教師 |
朱家瑩 |
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課號 |
LS5049 |
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課程識別碼 |
B21 U1700 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期四3,4(10:20~12:10) |
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上課地點 |
生科4C |
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備註 |
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1052LS5049_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
The role of RNA in regulating gene expression has become a topic of intense interest. This course will focus on RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in various model systems, including yeast, Drosophila, mammals, and viral infection. The course will also highlight the application of this knowledge in therapeutics and research at the final section.
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課程目標 |
This course will provide a comprehensive interpretation that is intended for students who are interest in RNA, the regulation of gene expression, genetics, genomics or molecular biology. |
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課程要求 |
Students are asked to develop a consolidated version of research proposal during the class, with a stepwise writing of abstract, research rationales, specific aims and the final proposal in different weeks. A final oral presentation is also required for each student. Grading standard is based on a mid-term quiz, the achievement of each assignment, and the oral presentation of research proposal. |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
待補 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
2/23 |
Organization/ Writing the Research Proposal |
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第2週 |
3/02 |
Introduction/ RNA in the nucleus |
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第3週 |
3/09 |
RNA splicing and processing |
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第4週 |
3/16 |
RNA editing and modification |
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第5週 |
3/23 |
RNA degradation |
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第6週 |
3/30 |
RNAi (I): eukaryotic RNAi |
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第7週 |
4/06 |
RNAi (II): prokaryotic RNAi |
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第8週 |
4/13 |
Invited talk |
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第9週 |
4/20 |
Small non-coding RNA (I): miRNAs and translational control in animals |
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第10週 |
4/27 |
Small non-coding RNA (II): piRNAs and RNA-directed DNA methylation |
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第11週 |
5/04 |
Long non-coding RNAs |
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第12週 |
5/11 |
Natural antisense and circular RNAs |
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第13週 |
5/18 |
Student Proposal Presentation (1) 黃馨巧、楊念澤、周少凱、何弘祥 |
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第14週 |
5/25 |
Student Proposal Presentation (2) Lulu、黃敏瑜、陳映辰 |
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第15週 |
6/01 |
Student Proposal Presentation (3) 林妤真、簡瑜君、楊明仁 |
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第16週 |
6/08 |
Student Proposal Presentation (4) 繆芳、徐振益、王昶欣 |
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第17週 |
6/15 |
Course wrap up |
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